LONDON: The HIV virus that causes AIDS, the fatal disease of the immune system, is becoming less aggressive, researchers have said in a landmark new study, amid surging speculation about the implications for the global fight against a pandemic that has killed an estimated 30 million people worldwide.
Researchers at the Institute of Tropical Medicine in Antwerp, Belgium, compared HIV-1 samples from 1986-89 and 2002-03 and found that 75 per cent of the newer samples appeared less fit than those of 15 years ago both in terms of spread within individuals and transmission to others.
Speaking to TOI from Antwerp, Dr Kevin Arien, who wrote the paper and is one of the lead researchers said: "From our study, based on 24 patient HIV-1 isolates, we have observed that historical viruses were more fit than recent HIV-1 isolates".
In layman's terms, explained Keith Alcorn, Senior Editor of National AIDS Manual, the UK's best scientific reference on HIV, that means "the virus is weakening and may be in 50 or a 100 years, it will adapt to living with its human host but cause less disease".
The study, titled 'Replicative fitness of historical and recent HIV-1 isolates suggests HIV-1 attenuation over time', is published in AIDS the official Journal of the International AIDS Society.
Source: Times of India (New Delhi)
Sunday, July 26, 2009
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